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Children are not miniature versions of adults. They are a heterogeneous group that differ developmentally, physiologically and psychologically from adults. The ongoing growth and maturation of organs affects both the disease course of asthma and the efficacy of medications. Consequently, asthma is a different disease in children than in adults and medications suitable for adults may not be successful in children. European Medicines Agency (EMEA)'s Committee on medicinal products for human use (CHMP) has ...

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bioequivalence.eu | | bioequivalence.eu Reviews

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Children are not miniature versions of adults. They are a heterogeneous group that differ developmentally, physiologically and psychologically from adults. The ongoing growth and maturation of organs affects both the disease course of asthma and the efficacy of medications. Consequently, asthma is a different disease in children than in adults and medications suitable for adults may not be successful in children. European Medicines Agency (EMEA)'s Committee on medicinal products for human use (CHMP) has ...

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bioequivalence.eu | | bioequivalence.eu Reviews

https://bioequivalence.eu

Children are not miniature versions of adults. They are a heterogeneous group that differ developmentally, physiologically and psychologically from adults. The ongoing growth and maturation of organs affects both the disease course of asthma and the efficacy of medications. Consequently, asthma is a different disease in children than in adults and medications suitable for adults may not be successful in children. European Medicines Agency (EMEA)'s Committee on medicinal products for human use (CHMP) has ...

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bioequivalence.eu

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Inhaled Corticosteroid | bioequivalence.eu

http://www.bioequivalence.eu/content/inhaled-corticosteroid

Bioequivalence between two inhaled corticosteroids. Safety investigations must be carried out following inhalation of the maximum recommended daily dose of the ICS regularly over time. Systemic safety should be demonstrated through pharmacokinetic bioequivalence and measurement of pharmacodynamic parameters. The current view in respect of the measurement of systemic effects of ICSs is to assess the effect on the hypothalamic pituitary adrenocortical. The hypothalamic pituitary adrenocortical.

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References | bioequivalence.eu

http://www.bioequivalence.eu/biblio

Regulation (EC) No 1901/2006 of the European Parliament and of the Council of 12 December 2006 on medicinal products for paediatric use. Drug Delivery to the Lung. Vol 162. Bisgaard H. Eds New York: Marcel Dekker; 2002. Drug delivery from inhaler devices. Professor Hans Bisgaard • Copenhagen • Denmark • Bisgaard@copsac.com.

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Aerosol Treatment of Children | bioequivalence.eu

http://www.bioequivalence.eu/content/aerosol-treatment-children

Aerosol Treatment of Children. Bioequivalence of novel aerosol and existing reference product needs documentation. This website present methods for such evidence based documentation of bioavailability of aerosol treatment of children. Drug Delivery to the Lung. Vol 162. Bisgaard H. Eds New York: Marcel Dekker; 2002. Professor Hans Bisgaard • Copenhagen • Denmark • Bisgaard@copsac.com.

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Devices | bioequivalence.eu

http://www.bioequivalence.eu/content/devices

Breath-operated metered dose inhalers. Drug Delivery to the Lungs (Ref 3). Differences between inhalation devices can cause several fold changes in efficacy as well as systemic bioavailability. Therefore, if a pMDI is to be used in children it must be developed for use together with a specific appropriate spacing device. Professor Hans Bisgaard • Copenhagen • Denmark • Bisgaard@copsac.com.

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Bioequvalence | bioequivalence.eu

http://www.bioequivalence.eu/content/bioequvalence

Two pharmaceutical products are bioequivalent if they are pharmaceutically equivalent and their bioavailabilities (rate and extent of availability) after administration in the same molar dose are similar to such a degree that their effects, with respect to both efficacy and safety, can be expected to be essentially the same. Therapeutic equivalence might be based on demonstration of equivalent drug distribution. Combined with bioequivalence based on pharmacokinetic data and/or pharmacodynamic data.

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asthmainchildren.org

Publications | COPSAC

http://www.asthmainchildren.org/biblio

Chawes, Bo L. Nadja H. Vissing. Ann-Marie M. Schoos. Helene M. Wolsk. Rebecca K. Vinding. Effect of Vitamin D3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial. 315, no. 4 (2016): 353-61. Felix, Janine F. Jonathan P. Bradfield. Ralf J. P. van der Valk. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. 25, no. 2 (2016): 389-403. Wolsk, Helene Mygind. Nilofar V. Følsgaard. Nadja H. Vissing.

asthmaandchildren.org

Site map | COPSAC

http://www.asthmaandchildren.org/sitemap

Vaccination of Pregnant Women. Synthetic Absorptive Matrix (SAM). This is a free tag vocabulary which contains the key words from all nodes created by the biblio module. COPSAC • Faculty of Health Sciences • University of Copenhagen • Denmark. Danish Pediatric Asthma Center • Copenhagen University Hospital. Ledreborg Alle 34 • 2820 Gentofte • phone 45 3977 7360 • contact@copsac.com.

asthmaandchildren.org

Publications | COPSAC

http://www.asthmaandchildren.org/biblio

Chawes, Bo L. Nadja H. Vissing. Ann-Marie M. Schoos. Helene M. Wolsk. Rebecca K. Vinding. Effect of Vitamin D3 Supplementation During Pregnancy on Risk of Persistent Wheeze in the Offspring: A Randomized Clinical Trial. 315, no. 4 (2016): 353-61. Felix, Janine F. Jonathan P. Bradfield. Ralf J. P. van der Valk. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. 25, no. 2 (2016): 389-403. Wolsk, Helene Mygind. Nilofar V. Følsgaard. Nadja H. Vissing.

asthmaandchildren.org

The COPSAC2010 Cohort | COPSAC

http://www.asthmaandchildren.org/content/copsacsub2010sub-cohort

Birth cohort is a population based longitudinal clinical study of 700 pregnant women and their offspring. It is the overriding objective to reduce the burden of disease from asthma and other wheezy disorders, eczema and allergy in young children and the long term impact to humans and society. Study builds on the comprehensive experience and knowledge gained from the COPSAC. Birth cohort, which has been monitored closely for 10 years. Building the novel COPSAC.

asthmaandchildren.org

Press And Interviews | COPSAC

http://www.asthmaandchildren.org/content/press-and-interviews

Trial Tests Effect of Vitamin D Supplementation During Pregnancy On Wheezing in Children. Hans Bisgaard is interviewed for Medical Research (January 27, 2016):. Read the interview here. Azithromycin Shortens Asthma Symptoms in Children. Hans Bisgaard is interviewed for Medical Research (January 20, 2016):. Read the interview here. Azithromycin Shotens 'Preschool Wheeze' Episodes: Study. Hans Bisgaard is interviewed for MedScape Peadiatrics (January 11, 2016):. Read the interview here. A supplement to Nat...

asthmaandchildren.org

Literature for parents | COPSAC

http://www.asthmaandchildren.org/content/literature-parents

These books are available both in English and Danish. Asthma in Young Children. This book explains what is known about asthma in young children, and how it should be treated. The more the parents can learn about the illness, the better they can understand their child’s reactions and thereby help the child in the best possible way. Click on the image to read the book. Asthma in children at the age of 7-18 years. Topical Steroids for Children with Asthma.

asthmainchildren.org

COPSAC Retreat | COPSAC

http://www.asthmainchildren.org/content/copsac-retreat

TRANSLATIONAL CLINICAL RESEARCH IN CHILDREN. Shared Origins in Early Life of Chronic Disorders. COPSAC Retreat, June 19. Of this 2-day retreat on the 19. Is PhD students and post-graduate researchers. At the final day a certificate of participation can be achieved. Will be at the scenic Sonnerupgaard Gods on the countryside of Zealand, about 45 min from Copenhagen. At] dbac [dot] dk. COPSAC • Faculty of Health Sciences • University of Copenhagen • Denmark.

asthmainchildren.org

Site map | COPSAC

http://www.asthmainchildren.org/sitemap

Vaccination of Pregnant Women. Synthetic Absorptive Matrix (SAM). This is a free tag vocabulary which contains the key words from all nodes created by the biblio module. COPSAC • Faculty of Health Sciences • University of Copenhagen • Denmark. Danish Pediatric Asthma Center • Copenhagen University Hospital. Ledreborg Alle 34 • 2820 Gentofte • phone 45 3977 7360 • contact@copsac.com.

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Children are not miniature versions of adults. They are a heterogeneous group that differ developmentally, physiologically and psychologically from adults. The ongoing growth and maturation of organs affects both the disease course of asthma and the efficacy of medications. Consequently, asthma is a different disease in children than in adults and medications suitable for adults may not be successful in children. European Medicines Agency (EMEA)'s Committee on medicinal products for human use (CHMP) has ...

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