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Monitoring mAb afucosylation using GlycINATOR. July 5, 2016 Applications. Liu, S. and Zang, L., 2016. Rapid quantitation of monoclonal antibody N-glyco-occupancy and afucosylation using mass spectrometry. Analytical Biochemistry, pp.1 10. Read more about GlycINATOR. Genovis and Promega sign global license agreement and settle litigation. June 30, 2016 Press Releases. FabULOUS Fab Kit – Intact Fab fragments from mouse IgG. June 7, 2016 Products. Digestion in the hinge with FabULOUS. Read more about FabULO...

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Monitoring mAb afucosylation using GlycINATOR. July 5, 2016 Applications. Liu, S. and Zang, L., 2016. Rapid quantitation of monoclonal antibody N-glyco-occupancy and afucosylation using mass spectrometry. Analytical Biochemistry, pp.1 10. Read more about GlycINATOR. Genovis and Promega sign global license agreement and settle litigation. June 30, 2016 Press Releases. FabULOUS Fab Kit – Intact Fab fragments from mouse IgG. June 7, 2016 Products. Digestion in the hinge with FabULOUS. Read more about FabULO...

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7 fc glycosylation

8 oxidation

9 deamidation

10 press release

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Genovis » Blog | blog.genovis.com Reviews

https://blog.genovis.com

Monitoring mAb afucosylation using GlycINATOR. July 5, 2016 Applications. Liu, S. and Zang, L., 2016. Rapid quantitation of monoclonal antibody N-glyco-occupancy and afucosylation using mass spectrometry. Analytical Biochemistry, pp.1 10. Read more about GlycINATOR. Genovis and Promega sign global license agreement and settle litigation. June 30, 2016 Press Releases. FabULOUS Fab Kit – Intact Fab fragments from mouse IgG. June 7, 2016 Products. Digestion in the hinge with FabULOUS. Read more about FabULO...

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blog.genovis.com

1

Genovis » Blog » New references on IgG glycosylation, glycation and ADC characterization using IgGZERO and FabRICATOR

http://blog.genovis.com/tag/adc

New references on IgG glycosylation, glycation and ADC characterization using IgGZERO and FabRICATOR. March 23, 2016 References. New references are out using Genovis enzymes to study antibody glycation, pairing of high-mannose glycans and ADC characterization using CE-MS. Generate and purify Fab fragments from human and mouse IgG using Genovis SmartEnzymes. Monitoring mAb afucosylation using GlycINATOR. EMEA & Asia. USA & Canada. Cambridge, MA 02142.

2

Genovis » Blog » GingisREX – New Enzyme from Genovis

http://blog.genovis.com/gingisrex-new-enzyme-from-genovis

GingisREX – New Enzyme from Genovis. April 14, 2016 Press Releases. Genovis expands the protease portfolio with GingisREX – a new enzyme with unique specificity for arginine residues. The GingisREX protease can be used for peptide mapping, protein sequencing and post-translational modification analysis using mass spectrometry. Read more about GingisREX. Generate and purify Fab fragments from human and mouse IgG using Genovis SmartEnzymes. Monitoring mAb afucosylation using GlycINATOR. EMEA & Asia.

3

Genovis » Blog » The Genovis team has published a review on FabRICATOR (IdeS) characterization of therapeutic antibodies

http://blog.genovis.com/the-genovis-team-has-published-a-review-on-fabricator-ides-characterization-of-therapeutic-antibodies

The Genovis team has published a review on FabRICATOR (IdeS) characterization of therapeutic antibodies. May 17, 2016 References. The Genovis team has together with Alain Beck, Senior Director Antibody Physico-Chemistry at Pierre Fabre, published a review article summarizing all the current publications using FabRICATOR (IdeS) for characterization of therapeutic antibodies and related products. Drug antibody ratio on ADCs. Learn more on the FabRICATOR enzyme. Find the publication here. EMEA & Asia.

4

Genovis » Blog » Genovis and Promega sign global license agreement and settle litigation

http://blog.genovis.com/category/press-releases

Articles in the Category Press Releases. Genovis and Promega sign global license agreement and settle litigation. June 30, 2016 Press Releases. Genovis has reached a settlement in its patent infringement lawsuit with Promega Corp. and agreed to a royalty bearing, worldwide license to the patents-in-suit. I am pleased we were able to reach a settlement with a favorable business solution that accommodates Genovis’ long term growth strategy, says Fredrik Olsson, CEO of Genovis. April 14, 2016 Press Releases.

5

Genovis » Blog » [New Reference] Using HILIC to study antibody subunits

http://blog.genovis.com/new-reference-using-hilic-to-study-antibody-subunits

New Reference] Using HILIC to study antibody subunits. April 26, 2016 Applications. Read more on this approach in Journal of Chromatography. More on the FabRICATOR enzyme. Generate and purify Fab fragments from human and mouse IgG using Genovis SmartEnzymes. Monitoring mAb afucosylation using GlycINATOR. EMEA & Asia. USA & Canada. Cambridge, MA 02142.

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genovis.com

Genovis Enzyme Reference Tool

http://www.genovis.com/Product%20references

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. FabRICATOR - removes the Fc domain by specific cleavage below the hinge region and generates an intact F(ab’)2 domain. Glycation is a non-enzymatic process where reducing sugars is added to lysine side chains ...

genovis.com

IgGZERO (EndoS)

http://www.genovis.com/IgGZERO%20(EndoS)

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. IgGZERO is used to rapidly deglycosylate antibodies to reduce sample complexity or to inactivate Fc-mediated effector functions. Ldquo;i like the column formate for the IgGZERO. Rapid - 30 min deglycosylation.

genovis.com

GlycINATOR (EndoS2)

http://www.genovis.com/GlycINATOR-(EndoS2)

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. GlycINATOR is an endoglycosidase (EndoS2) from. GlycINATOR can be used in combination with IgGZERO and FabRICATOR. Is a useful tool for us involved in protein analysis. Cleaves all N-linked glycans on IgG.

genovis.com

Genovis Enzymes for Antibodies

http://www.genovis.com/home

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. Nyemission den 23 maj-8 juni. New Arg Specific Protease for Proteomics. Genovis ranks among “50 Fastest-Growing" technology companies” in Sweden, Second Year In A Row. Sept 14-15, 2016. Sept 28-29, 2016. Compa...

genovis.com

Genovis - Applications

http://www.genovis.com/Applications

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. Here you find information about how you can use Genovis' products in your application. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Multiple sites in Fc.

genovis.com

Genovis How to Order

http://www.genovis.com/How-to-order

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. Here you can find information regarding placing orders at Genovis. And here for EMEA and Asia. If you have any questions, please don't hesitate to contact us filling out this form. Or give us a call. If you wi...

genovis.com

FabRICATOR Z IdeZ protease

http://www.genovis.com/FabRICATOR_Z

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. FabRICATOR Z (IdeZ) is a homologue to FabRICATOR with increased activity on mouse IgG2a that specifically cut the antibody just below the hinge region. FabRICATOR Z, derived from. FragIT Z and FragIT Z Kit.

genovis.com

IdeS Protease - FabRICATOR Enzyme - Antibody fragmentation

http://www.genovis.com/FabRICATOR%20(IdeS)

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. FabRICATOR (IdeS) is a unique enzyme that specifically digests the hinge region of IgG, producing a F(ab’)2 fragment and two Fc fragments. FabRICATOR is a recombinantly modified form of IdeS from. Excellent yi...

genovis.com

GingisKHAN KGP protease

http://www.genovis.com/GingisKHAN

FragIT and FragIT Kit. FragIT Z and FragIT Z Kit. Antibody Drug Conjugates Characterization. FabRICATOR in QC applications. MAb Quality in Cell Culture. Mass Spectrometric Analysis of Antibodies. Mass Spectrometric Analysis of Antibodies. Production of Fab Fragments. Generation of F(ab)2 Fragments. Trade; is outstanding for preparation of intact Fab fragments". Specific - one precise cleavage site in upper hinge of human IgG1. Rapid – 60 minute protocol for complete digestion. All published papers on how...

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Genovis » Blog

Monitoring mAb afucosylation using GlycINATOR. July 5, 2016 Applications. Liu, S. and Zang, L., 2016. Rapid quantitation of monoclonal antibody N-glyco-occupancy and afucosylation using mass spectrometry. Analytical Biochemistry, pp.1 10. Read more about GlycINATOR. Genovis and Promega sign global license agreement and settle litigation. June 30, 2016 Press Releases. FabULOUS Fab Kit – Intact Fab fragments from mouse IgG. June 7, 2016 Products. Digestion in the hinge with FabULOUS. Read more about FabULO...

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塩原温泉お出かけ日記（秘湯の宿元泉館ブログ）

JR東日本びゅうブランド地温泉湯守の会. JR東日本びゅうブランド地温泉湯守の会. JR東日本びゅうブランド地温泉湯守の会. この度、秘湯の宿元泉館は、JR東日本びゅうブランド、地温泉湯守の会に加入させていただきました。地温泉湯守の会ブランドのご予約は、お近くのびゅうトラベルサービスをご利用ください。 JR東日本びゅうブランド地温泉湯守の会. 日時: 2018年2月 5日 17:47. 日時: 2018年1月 1日 13:00. 日時: 2017年12月 3日 11:00. 秘湯の宿元泉館では、3種類の地酒が楽しめる栃木の銘酒利き酒セット税込み１２９６円をご用意しております。銘柄は、大田原市のホーラン酒造の本醸造ほうらん日本酒度１、矢板市森戸酒造の本醸造たかはら日本酒度２、大田原市菊の里酒造のとちぎにごり湯の会にごり酒日本酒度１です。日時: 2017年12月 2日 12:41.