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Home Page - LiverTox Case Registry

We welcome the site visitor to submit a clinical case of drug induced liver injury to LiverTox on-line. The web site provides prompts to enter the essential clinical information and provides a means of printing out the submitted data and a written summary of the case in text with a table or a graph. The summary is a concise description of the case that can be added to a patient chart or as a consultant note. The summary also includes calculation of helpful factors, such as the time to onset and recovery,

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We welcome the site visitor to submit a clinical case of drug induced liver injury to LiverTox on-line. The web site provides prompts to enter the essential clinical information and provides a means of printing out the submitted data and a written summary of the case in text with a table or a graph. The summary is a concise description of the case that can be added to a patient chart or as a consultant note. The summary also includes calculation of helpful factors, such as the time to onset and recovery,
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Home Page - LiverTox Case Registry | livertox.niddk.nih.gov Reviews

https://livertox.niddk.nih.gov

We welcome the site visitor to submit a clinical case of drug induced liver injury to LiverTox on-line. The web site provides prompts to enter the essential clinical information and provides a means of printing out the submitted data and a written summary of the case in text with a table or a graph. The summary is a concise description of the case that can be added to a patient chart or as a consultant note. The summary also includes calculation of helpful factors, such as the time to onset and recovery,

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1

Reference Cases - LiverTox Case Registry

https://livertox.niddk.nih.gov/Home/ReferenceCases

Skip to page content. Clinical and Research Information on Drug-Induced Liver Injury. Drag a column header and drop it here to group by that column. Patient (Click to Open). 51 year old man. 3 : Moderately Severe. 57 year old woman. 60 year old woman. 58 year old woman. 67 year old woman. 66 year old woman. 22 year old woman. 48 year old woman. 70 year old woman. 65 year old woman. 1 - 10 of 131 items. Https:/ livertox.niddk.nih.gov/Home/ReferenceCases. US Department of Health and Human Services.

2

Important Elements to include in Reporting Cases of Drug-induced Liver Injury - LiverTox Case Registry

https://livertox.niddk.nih.gov/Home/ImportantElements

Skip to page content. Clinical and Research Information on Drug-Induced Liver Injury. Important Elements to include in Reporting Cases of Drug-induced Liver Injury. Name of the medication (generic name). Dose and regimen of its administration. Date that the Medication was Started. Date that the Medication was Stopped (or Duration of Therapy). Date of first onset of symptoms of liver injury or blood test abnormalities (or time to onset). IgM anti-HAV to exclude hepatitis A. Previous history of exposure to...

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Clinical Outcomes

http://livertox.nih.gov/ClinicalOutcome.html

Vanishing Bile Duct Syndrome. Submit a Case Report. Most cases of drug induced liver injury ultimately resolve completely without residual liver injury or liver test abnormalities. Three major exceptions include the progression to acute liver failure. The evolution to vanishing bile duct syndrome. And development of chronic liver injury and cirrhosis. US National Library of Medicine. 8600 Rockville Pike, Bethesda, MD 20894. National Institutes of Health. US Department of Health and Human Services.

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Search Livertox Database

http://livertox.nih.gov/index.html

Submit a Case Report. SEARCH THE LIVERTOX DATABASE. Search for a specific medication,. Browse by first letter of medication,. Provides up-to-date, accurate, and easily accessed information on the diagnosis, cause, frequency, patterns, and management of liver injury attributable to prescription and nonprescription medications, herbals and dietary supplements. L IVER. For more information about L IVER. US National Library of Medicine. 8600 Rockville Pike, Bethesda, MD 20894. National Institutes of Health.

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Likelihood Scale

http://livertox.nih.gov/DrugCategory.html

Submit a Case Report. CATEGORIZATION OF THE LIKELIHOOD. OF DRUG INDUCED LIVER INJURY. Medications can be categorized for the likelihood that they are associated with drug induced liver injury based upon their known potential for causing such injury. This categorization is important in assessing causality and is based largely upon what has been published in the medical literature. At present there is no accepted classification of drugs based upon this likelihood. The drug is well known,. Despite extensive...

livertox.nlm.nih.gov livertox.nlm.nih.gov

Likelihood Scale

https://livertox.nlm.nih.gov/DrugCategory.html

Submit a Case Report. CATEGORIZATION OF THE LIKELIHOOD. OF DRUG INDUCED LIVER INJURY. Medications can be categorized for the likelihood that they are associated with drug induced liver injury based upon their known potential for causing such injury. This categorization is important in assessing causality and is based largely upon what has been published in the medical literature. At present there is no accepted classification of drugs based upon this likelihood. The drug is well known,. Despite extensive...

livertox.nlm.nih.gov livertox.nlm.nih.gov

Conference Proceedings

https://livertox.nlm.nih.gov/proceeding.html

Submit a Case Report. THE LIVER MEETING 2016. American Association for the Study of Liver Diseases. Hynes Veterans Memorial Convention Center, Boston, MA. November 11-15, 2016. Sponsored by the American Association for the Study of Liver Diseases (AASLD), the Meeting has a focus on the science and practice of hepatology, providing the latest information on hepatology research and patient care. LIVER INJURY FROM HERBAL AND DIETARY SUPPLEMENTS. Lister Hill Auditorium, NIH Campus, Bethesda, MD. May 4-5, 2015.

livertox.nlm.nih.gov livertox.nlm.nih.gov

Clinical Course

https://livertox.nlm.nih.gov/ClinicalCourse.html

Exclusion of Other Diagnoses. Known Cause of Injury. Submit a Case Report. CLINICAL COURSE AND DIAGNOSIS. OF DRUG INDUCED LIVER DISEASE. Signs and patterns of liver test abnormalities. Of drug induced liver injury can mimic virtually any form of liver disease – from acute viral hepatitis. To gall stone disease with biliary obstruction, acute fatty liver. And even chronic hepatitis and cirrhosis. In judging the likelihood of drug induced liver disease, six features are important:. The time to recovery rep...

livertox.nih.gov livertox.nih.gov

Abbreviations used in LiverTox

http://livertox.nih.gov/abbreviation.html

Submit a Case Report. ABBREVIATIONS USED IN LIVERTOX. The LiverTox website is written to provide comprehensive and clear information on the hepatotoxicity. Antibody to hepatitis A virus. Antibody to hepatitis B core antigen. Antibody to hepatitis B e antigen. Antibody to hepatitis B surface antigen. Antibody to hepatitis C virus. Centers for Disease Control and Prevention. Drug Induced Liver Injury Network. Food and Drug Administration. Hepatitis B e antigen. Hepatitis B surface antigen.

livertox.nih.gov livertox.nih.gov

Clinical Course

http://livertox.nih.gov/ClinicalCourse.html

Exclusion of Other Diagnoses. Known Cause of Injury. Submit a Case Report. CLINICAL COURSE AND DIAGNOSIS. OF DRUG INDUCED LIVER DISEASE. Signs and patterns of liver test abnormalities. Of drug induced liver injury can mimic virtually any form of liver disease – from acute viral hepatitis. To gall stone disease with biliary obstruction, acute fatty liver. And even chronic hepatitis and cirrhosis. In judging the likelihood of drug induced liver disease, six features are important:. The time to recovery rep...

livertox.nih.gov livertox.nih.gov

Severity Grading

http://livertox.nih.gov/Severity.html

Submit a Case Report. IN DRUG INDUCED LIVER INJURY. The severity of cases of drug induced liver injury can vary greatly, from mild, transient and asymptomatic elevations in serum enzyme levels to acute liver failure. Leading rapidly to death or need for liver transplantation. Hospitalization, signs of hepatic or other organ failure, and ultimate outcome. Raised serum aminotransferase or alkaline phosphatase levels or both, but total serum bilirubin. 25 mg/dL and no coagulopathy. 2 , Moderate. 4 , Severe.

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Home Page - LiverTox Case Registry

Skip to page content. Clinical and Research Information on Drug-Induced Liver Injury. A guide to reporting a case of drug-induced liver disease. Reporting a Case to MedWatch. The case of drug-induced liver injury should also be reported to the Food and Drug Administration (FDA). Reports to the FDA are easy to prepare and represent responsible citizenship. The reporting is to "MedWatch" which can be done on line at www.fda.gov/Safety/MedWatch. Reporting a case to LiverTox. Jay H Hoofnagle, MD.

livertox.nih.gov livertox.nih.gov

Search Livertox Database

Submit a Case Report. SEARCH THE LIVERTOX DATABASE. Search for a specific medication,. Browse by first letter of medication,. Provides up-to-date, accurate, and easily accessed information on the diagnosis, cause, frequency, patterns, and management of liver injury attributable to prescription and nonprescription medications, herbals and dietary supplements. L IVER. For more information about L IVER. US National Library of Medicine. 8600 Rockville Pike, Bethesda, MD 20894. National Institutes of Health.

livertox.nlm.nih.gov livertox.nlm.nih.gov

Search Livertox Database

Submit a Case Report. SEARCH THE LIVERTOX DATABASE. Search for a specific medication,. Browse by first letter of medication,. Provides up-to-date, accurate, and easily accessed information on the diagnosis, cause, frequency, patterns, and management of liver injury attributable to prescription and nonprescription medications, herbals and dietary supplements. L IVER. For more information about L IVER. US National Library of Medicine. 8600 Rockville Pike, Bethesda, MD 20894. National Institutes of Health.

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