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The Brent Lab | Home

The Brent Lab is developing and applying computational methods for mapping gene regulation networks, modeling them quantitatively, and engineering new behaviors into them. Mapping Transciption Factor Networks. We develop efficient methods for determining which transcription factors can bind and regulate each gene in a genome. Modeling Dynamic Transciption Factor Networks. Understanding the relationship between binding and regulation. Capsule Regulation and Virulence in Cryptococcus Neoformans.

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The Brent Lab | Home | mblab.wustl.edu Reviews

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The Brent Lab is developing and applying computational methods for mapping gene regulation networks, modeling them quantitatively, and engineering new behaviors into them. Mapping Transciption Factor Networks. We develop efficient methods for determining which transcription factors can bind and regulate each gene in a genome. Modeling Dynamic Transciption Factor Networks. Understanding the relationship between binding and regulation. Capsule Regulation and Virulence in Cryptococcus Neoformans.

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1 people

2 research

3 publications

4 news and events

5 software

6 collaborators and funding

7 research focus

8 transcriptome engineering

9 the brent lab

10 email brent at wustl edu

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The Brent Lab | Home | mblab.wustl.edu Reviews

https://mblab.wustl.edu

The Brent Lab is developing and applying computational methods for mapping gene regulation networks, modeling them quantitatively, and engineering new behaviors into them. Mapping Transciption Factor Networks. We develop efficient methods for determining which transcription factors can bind and regulate each gene in a genome. Modeling Dynamic Transciption Factor Networks. Understanding the relationship between binding and regulation. Capsule Regulation and Virulence in Cryptococcus Neoformans.

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mblab.wustl.edu

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The Brent Lab | People

http://mblab.wustl.edu/people.html

Michael Brent, PhD. Professor of Computer Science. Joint Appointments in Genetics and BME. The Henry Edwin Sever Professor of Engineering. Undergraduate Researcher, 2012-2013. Graduate Student, Harvard. Undergraduate Researcher, 2011-2013. Undergraduate Researcher, 2012-2013. Graduate Student, Harvard. Graduate Student, 2008-2012. Senior Scientist, Assuragen Inc. Email: brian.c.haynes@gmail.comm. Research Technician, 2008-2011. Graduate Student, MIT. Undergraduate Researcher, 2010-2012. Ian Korf, Ph.D.

2

The Brent Lab | Publications

http://mblab.wustl.edu/publications.html

Click here for Michael Brent's full publications list from Google Scholar.

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The Brent Lab | Collaborators & Funding

http://mblab.wustl.edu/collaborators.html

Capsule Regulation and Virulence in Cryptococcus Neoformans. Http:/ endo.wustl.edu/faculty/baranski.html. Regulatory Network Modeling of Diet-induced Diabetes in the Fly. Http:/ www.ucdenver.edu/academics/./JohnstonM.aspx. Linking Gene Regulation to Metabolism. Center for Genome Sciences and Systems Biology. 4515 McKinley Ave., 4th floor, Room 4703. St Louis, MO 63110. Tel: 314.286.0210. Fax: 314.935.7302. Thanks to OS Templates.

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The Brent Lab | News & Events

http://mblab.wustl.edu/news.html

Center for Genome Sciences and Systems Biology. 4515 McKinley Ave., 4th floor, Room 4703. St Louis, MO 63110. Tel: 314.286.0210. Fax: 314.935.7302. Thanks to OS Templates.

5

The Brent Lab | Software

http://mblab.wustl.edu/software.html

NetSurgeon is a novel algorithm for transcriptome engineering - designing transcription-factor deletions or over-expressions to move cells to a gene expression state that is associated with a desired phenotype. Michael, D.G., Maier, E.J. Brown, H., Gish, S.R., Fiore, C., Brown, R.H., and Brent, M.R. In Review. "Model-based Transcriptome Engineering Promotes a Fermentative Transcriptional State in Yeast.". Beta release of NetSurgeon. Netsurgeon 0.1.tar.gz. Beta release of NetProphet. PhenoProphet is a nov...

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genomesciences.wustl.edu

Center for Genome Sciences & Systems Biology - Washington University School of Medicine

https://genomesciences.wustl.edu/CGSFaculty.htm

Jeffrey Gordon — Center Director. Genomic and metabolic foundations of symbiotic host-microbial relationships in the mammalian gut. Lab Website. Megan's research explores the regulation of viral and bacterial pathogens by commensal bacteria and the host innate immune system. Her lab also characterizes how pathogens evolve to evade host control and benefit from the presence of other microbes. Lab Website. Barak Cohen - Ruffian, Scallywag, Systems Biologist. As a pediatric oncologist, Todd's research is fo...

machinelearning.wustl.edu

Machine Learning @ Wash U. Main/Faculty

http://machinelearning.wustl.edu/pmwiki.php/Main

Machine Learning @ Wash U. Kilian Q. Weinberger. Edwin T. Jaynes. Current Ph.D. Students. A list of machine learning courses offered. Page last modified on August 20, 2015, at 04:56 PM. Theme adapted by David Gilbert.

machinelearning.wustl.edu

Machine Learning @ Wash U. Main/Faculty

http://machinelearning.wustl.edu/pmwiki.php/Main/Faculty

Machine Learning @ Wash U. Kilian Q. Weinberger. Edwin T. Jaynes. Current Ph.D. Students. A list of machine learning courses offered. Page last modified on August 20, 2015, at 04:56 PM. Theme adapted by David Gilbert.

machinelearning.wustl.edu

Machine Learning @ Wash U. Main/Faculty

http://machinelearning.wustl.edu/pmwiki.php

Machine Learning @ Wash U. Kilian Q. Weinberger. Edwin T. Jaynes. Current Ph.D. Students. A list of machine learning courses offered. Page last modified on August 20, 2015, at 04:56 PM. Theme adapted by David Gilbert.

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The Brent Lab | Home

The Brent Lab is developing and applying computational methods for mapping gene regulation networks, modeling them quantitatively, and engineering new behaviors into them. Mapping Transciption Factor Networks. We develop efficient methods for determining which transcription factors can bind and regulate each gene in a genome. Modeling Dynamic Transciption Factor Networks. Understanding the relationship between binding and regulation. Capsule Regulation and Virulence in Cryptococcus Neoformans.

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