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neherlab | Richard Neher's lab: HIV evolution and population genetics

Richard Neher's lab: HIV evolution and population genetics

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neherlab | Richard Neher's lab: HIV evolution and population genetics | neherlab.wordpress.com Reviews

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Richard Neher's lab: HIV evolution and population genetics

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1

Which flu strain will dominate 2015/2016? – neherlab

https://neherlab.wordpress.com/2015/01/09/which-flu-strain-will-dominate-20152016

Evolution, population genetics, and infectious diseases. Which flu strain will dominate 2015/2016? In November, Boris Shraiman. And myself published a paper on predicting evolution. Building on two projects by Trevor Bedford. To automatically construct influenza trees ( augur. And visualize them using javascript ( augur. I developed a tool for interactive exploration of seasonal influenza evolution and prediction. The dynamics of A/H3N2 viruses over the last 3 years are illustrated in the above figure&#4...

2

Is evolution predictable? – neherlab

https://neherlab.wordpress.com/2014/06/05/is-evolution-predictable

Evolution, population genetics, and infectious diseases. 8212; a collaboration with Colin Russell. How does it work? Individuals adapt to a changing environment by accumulating beneficial mutations, while avoiding deleterious mutations. We model this process assuming that there are many such mutations which change fitness in small increments. Using this model, we calculate the probability that an individual that lived in the past at time. And with an individual B that lived at a later time. The joint pro...

3

nextflu.org – neherlab

https://neherlab.wordpress.com/2015/02/23/nextflu-org

Evolution, population genetics, and infectious diseases. Together with Trevor Bedford. I have been working on a new version of the interactive tool to explore influenza evolution. It is now up and running at http:/ nextflu.org. In addition to a tree of the most recent influenza strains, we now also include frequencies of mutations, more complex genotypes, and clades of the tree. February 23, 2015. February 23, 2015. Leave a Reply Cancel reply. Enter your comment here. Address never made public).

4

neherlab – Page 2 – Evolution, population genetics, and infectious diseases

https://neherlab.wordpress.com/page/2

Evolution, population genetics, and infectious diseases. Taylor successfully defended his thesis! Picture by Emmanuel Benard. December 9, 2015. December 9, 2015. Leave a comment on Taylor successfully defended his thesis! HInextflu.org visualizes antigenic evolution of influenza viruses. In a new preprint. And myself, we show how antigenic evolution can be integrated with the phylogenetic tree of HA sequences. Mutations with antigenic effects highlighted on a HA structure. Results from such assays come i...

5

Now out in eLife: Predicting evolution – neherlab

https://neherlab.wordpress.com/2014/11/11/now-out-in-elife-predicting-evolution

Evolution, population genetics, and infectious diseases. Now out in eLife: Predicting evolution. On predicting evolution ( see also this earlier post. How the Local Branching Index (LBI) works: Consider the rooted tree on the left and the corresponding unrooted tree (the root is indicated by the black dot). The LBI of the node connecting the orange and red clade is the length of the tree in the shaded area. The more rapidly the tree is branching close to this node, the larger is the LBI. November 11, 2014.

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Ebola paper in Cell | Andersen Lab

http://andersen-lab.com/new-ebola-paper-out-in-cell

Dudes & Dudettes. Dudes & Dudettes. Ebola paper out in Cell. June 18, 2015. In a large collaboration between the Viral Hemorrhagic Fever Consortium, Kenema Government Hospital, Harvard University, Broad Institute, Tulane University, Edinburgh University, the CDC, USAMRIID, and others we have just published a paper in. Detailing the epidemiology, transmission, and evolution of Ebola virus over seven months in Sierra Leone. The new study sequenced 232 new Ebola virus genomes, which were all released on NCBI.

bedford.io bedford.io

bedford lab / blog

http://bedford.io/blog

Zika sequencing in Brazil (or Trevor does fieldwork). 10 Jun 2016 by trvrb. I'm at the Rio airport now, heading home after 9 days in Brazil as part of the ground team of the ZiBRA project. As part of the team, I traveled from Natal to Recife along the northeastern coast collecting clinical samples for mobile Zika genome sequencing and analysis. This has been an illuminating experience and I'm grateful to Nick. And the rest of the team. For inviting me to be part of this. The RT diagnostic is particularly...

hi.nextflu.org hi.nextflu.org

Seasonal influenza circulation patterns and future projections

http://hi.nextflu.org/reports/sep-2015

Real-time tracking of seasonal influenza. Virus evolution in humans. Seasonal influenza circulation patterns and future projections. September 16, 2015. This is not meant as a comprehensive report, but is instead intended as particular observations that we've made that may be of relevance. Please also note that observed patterns reflect the GISAID database and may not be entirely representative of underlying dynamics. Summarizing data from recent reports by the WHO CC London. Thus, 3c2.a and 3c3....We ob...

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Richard Neher's lab: HIV evolution and population genetics. Skip to primary content. Skip to secondary content. June 12, 2015. About 3 years ago, a novel respiratory disease was diagnosed in Saudi Arabia and called Middle East Respiratory Syndrome. Sequences of recently isolated viruses from China and Korea have been deposited in genbank this week. To track the spread and evolution of the virus, we adapted nextflu. To MERS-CoV. This is now live at mers.nextflu.org. February 23, 2015. I have been working ...

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