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The Sanders Lab

My lab uses Protein X-ray Crystallography to determine the atomic structures of proteins and seeks to understand the relationship between protein structure and function. Besides crystallography we utilize other approaches including enzymology, spectroscopy, protein expression, drug discovery, molecular genetics and related techniques. Dr Sanders' Research Lab, Department of Chemistry. 110 Science Place, University of Saskatchewan, Saskatoon, Canada. PH: 306-966-6788 FX: 306-966-4730.

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The Sanders Lab | prospero.usask.ca Reviews

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My lab uses Protein X-ray Crystallography to determine the atomic structures of proteins and seeks to understand the relationship between protein structure and function. Besides crystallography we utilize other approaches including enzymology, spectroscopy, protein expression, drug discovery, molecular genetics and related techniques. Dr Sanders' Research Lab, Department of Chemistry. 110 Science Place, University of Saskatchewan, Saskatoon, Canada. PH: 306-966-6788 FX: 306-966-4730.

<META> KEYWORDS

1 research interests

2 publications

3 lab members

4 structures

5 links

6 photos

7 dept of chemistry

8 canadian light source

9 prism homepage

10 dept of biochemistry

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The Sanders Lab | prospero.usask.ca Reviews

https://prospero.usask.ca

My lab uses Protein X-ray Crystallography to determine the atomic structures of proteins and seeks to understand the relationship between protein structure and function. Besides crystallography we utilize other approaches including enzymology, spectroscopy, protein expression, drug discovery, molecular genetics and related techniques. Dr Sanders' Research Lab, Department of Chemistry. 110 Science Place, University of Saskatchewan, Saskatoon, Canada. PH: 306-966-6788 FX: 306-966-4730.

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prospero.usask.ca

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The Sanders Lab

http://prospero.usask.ca/images.html

Sanders' Lab Structure Gallery. This work reported the crystal structure of UDP-galactose-4-epimerase from. Complexed with NAD and UDP-glucose. In addition, we examined the determinants of substrate specificity and used docking studies to rationalize the binding of UDP-galactose and UDP-N-acetyl-galactosamine. PLoS One (2013) accepted August 29th, 2013. Dalrymple, S.A., Ko, J., Sheoran, I., Kaminskyj, S.G.W. and Sanders, D.A.R. UDP-galactose-4-epimerase from Aspergillus nidulans. This is the first report...

2

The Sanders Lab

http://prospero.usask.ca/publications.html

58 Sahtout, N., Kuttiyatveetil, J.R.A., Fodje, M. and Sanders, D.A.R. Putative Thioredoxin Trx1 from Thermosipho africanus. Strain TCF52B: Expression, Purification and Structural Determination using S-SAD. 57 Skovpen, Y.V., Conly, C.J.T., Sanders, D.A.R. And Palmer, D.R.J.* ( 2016. Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. J Am Chem Soc. And Pinto, B.M. * ( 2015. Ravindranathan Kartha, K.P., Pinto, B.M.* ( 2015. J Am Chem Soc.

3

The Sanders Lab

http://prospero.usask.ca/home.html

My lab uses Protein X-ray Crystallography to determine the atomic structures of proteins and seeks to understand the relationship between protein structure and function. Besides crystallography we utilize other approaches including enzymology, spectroscopy, protein expression, drug discovery, molecular genetics and related techniques. Dr Sanders' Research Lab, Department of Chemistry. 110 Science Place, University of Saskatchewan, Saskatoon, Canada. PH: 306-966-6788 FX: 306-966-4730.

4

Sanders Lab Photos

http://prospero.usask.ca/gallery.php

ACA 2009 - Toronto. ACA 2010 - Chicago. ACA 2012 - Boston. Poster displays at CSC 2120, Calgary AB, Photos courtesy of Dave Palmer. IUCr 2011 - Madrid, Spain.

5

The Sanders Lab

http://prospero.usask.ca/links.html

International Union of Crystallography(IUCr). U of S Pages. Canadian Macromolecular Crystallography Facility (CLS). PDB Files - Internal. U of S Library. Acta Crystallographica Section D. Journal of Biological Chemistry. Acta Crystallographica Section F. Proteins : Structure, Function and Bioinformatics. Protein Topology - Cartoon. Dr David Palmer, Department of Chemistry, U of S. Dr Peta Bonham-Smith, Department of Biology, U of S. Dr Jim Naismith, St. Andrews University, Scotland. DSSP - Definitions of...

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prism.usask.ca

Members - University of Saskatchewan

http://prism.usask.ca/people/members/index.php

PRISM - Proteomics Research in Interactions and Structure of Macromolecules. Protein Characterization and Crystallization Facility. Cancer Cluster shared equipment. College of Pharmacy and Nutrition. Microbiology and Immunology, College of Medicine. Plant Sciences, College of Agriculture and BioResources. Biochemistry, College of Medicine. Biochemistry, College of Medicine. Pathology, College of Medicine. Pathology, College of Medicine. Anatomy and Cell Biology, College of Medicine.

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The Sanders Lab

My lab uses Protein X-ray Crystallography to determine the atomic structures of proteins and seeks to understand the relationship between protein structure and function. Besides crystallography we utilize other approaches including enzymology, spectroscopy, protein expression, drug discovery, molecular genetics and related techniques. Dr Sanders' Research Lab, Department of Chemistry. 110 Science Place, University of Saskatchewan, Saskatoon, Canada. PH: 306-966-6788 FX: 306-966-4730.

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