seneslab.org

The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison

Structure, folding and design of integral membrane proteins. What is the biophysical basis of transmembrane helix-helix interaction? We are interested in investigating this process and in developing methods for predicting and designing oligomeric complexes of transmembrane helices. May 11, 2015. Congratulations to Ben Mueller for successfully defending her PhD thesis in Biochemistry. April 23, 2015. Dec 15, 2014. Three new PhD students join the lab! Dec 1, 2014. Congratulations to Loren LaPointe for succ...

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The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison | seneslab.org Reviews

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Structure, folding and design of integral membrane proteins. What is the biophysical basis of transmembrane helix-helix interaction? We are interested in investigating this process and in developing methods for predicting and designing oligomeric complexes of transmembrane helices. May 11, 2015. Congratulations to Ben Mueller for successfully defending her PhD thesis in Biochemistry. April 23, 2015. Dec 15, 2014. Three new PhD students join the lab! Dec 1, 2014. Congratulations to Loren LaPointe for succ...

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1 research

2 publications

3 people

4 alumni

5 software

6 lab wiki

7 news

8 dr ben

9 congratulations fellowship recepients

10 dr loren

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The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison | seneslab.org Reviews

https://seneslab.org

Structure, folding and design of integral membrane proteins. What is the biophysical basis of transmembrane helix-helix interaction? We are interested in investigating this process and in developing methods for predicting and designing oligomeric complexes of transmembrane helices. May 11, 2015. Congratulations to Ben Mueller for successfully defending her PhD thesis in Biochemistry. April 23, 2015. Dec 15, 2014. Three new PhD students join the lab! Dec 1, 2014. Congratulations to Loren LaPointe for succ...

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seneslab.org

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The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison

http://www.seneslab.org/publications.html

Armstrong CR, Senes A. Screening for transmembrane association in divisome proteins using TOXGREEN, a high-throughput variant of the TOXCAT assay". Biochim. Biophys. Acta. Barth P, Senes A. Toward high-resolution computational design of the structure and function of helical membrane proteins". Nat Struct Mol Biol. The computational design of α-helical membrane proteins is still in its infancy but has already made great progress. De novo design allows stable, specific and active minimal oligomer...Store d...

2

The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison

http://www.seneslab.org/EBL.html

The Energy-Based Conformer Library (EBL). Subramaniam S and Senes A. An Energy-Based conformer library for side chain optimization: improved prediction and adjustable sampling". DOI: 10.1002/prot.24111. The library introduces a number of new features and properties in the selection of conformes for side chain optimization. The library is sorted by the efficiency of the conformer in fitting natural protein environments. All four files, zip compressed: EBL.zip. C) for hydrogen bonding, the hydrogen bond pa...

3

The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison

http://www.seneslab.org/software.html

MSL (Molecular Software Libraries). MSL is an open source C library for analysis, manipulation, modeling and design of macromolecules. For download and documentation go to the MSL project wiki. 433 Backcock Dr., Room 419. Madison, WI 53706. Office ( 1) 608-890-2584. Lab ( 1) 608-262-7355.

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The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison

http://www.seneslab.org/alumni.html

In reverse chronological order. PhD program in Biochemistry. Jan 2009 - Feb. 2016 (from Jan. 2015 to Feb. 2016 as a postdoc). FRET-based biophysical characterization of bacterial divisome transmembrane proteins" [ PDF. Postdoc in Mike Ramsey's lab. University of North Carolina at Chapel Hill. LaPointe LM, Taylor KC, Subramaniam S, Khadria A. Rayment I and Senes A "Structural organization of FtsB, a transmembrane protein of the bacterial divisome", Biochemistry. PhD program in Biochemistry. Subramaniam S*...

5

The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison

http://www.seneslab.org/index.html

Structure, folding and design of integral membrane proteins. What is the biophysical basis of transmembrane helix-helix interaction? We are interested in investigating this process and in developing methods for predicting and designing oligomeric complexes of transmembrane helices. May 11, 2015. Congratulations to Ben Mueller for successfully defending his PhD thesis in Biochemistry. Ben will move to the lab of Jens Meiler. At Vanderbilt University at the end of the summer. April 23, 2015. Dec 15, 2014.

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The Senes Lab, Department of Biochemistry, University of Wisconsin-Madison

Structure, folding and design of integral membrane proteins. What is the biophysical basis of transmembrane helix-helix interaction? We are interested in investigating this process and in developing methods for predicting and designing oligomeric complexes of transmembrane helices. May 11, 2015. Congratulations to Ben Mueller for successfully defending her PhD thesis in Biochemistry. April 23, 2015. Dec 15, 2014. Three new PhD students join the lab! Dec 1, 2014. Congratulations to Loren LaPointe for succ...

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