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Kryazhimskiy lab

Kryazhimskiy Lab @ UCSD. We are interested in uncovering general principles of how mutations affect phenotypes at multiple levels of biological organization (gene expression, metabolic fluxes, etc.), and how these effects combine to determine organism’s fitness across environments. We approach this problem using experiments in model microorganisms. Soon) and mathematical modeling. October 20, 2016. October 11, 2016. First SK Lab meeting! Georg presents his future project. October 3, 2016.

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Kryazhimskiy lab | sklab.science Reviews

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Kryazhimskiy Lab @ UCSD. We are interested in uncovering general principles of how mutations affect phenotypes at multiple levels of biological organization (gene expression, metabolic fluxes, etc.), and how these effects combine to determine organism’s fitness across environments. We approach this problem using experiments in model microorganisms. Soon) and mathematical modeling. October 20, 2016. October 11, 2016. First SK Lab meeting! Georg presents his future project. October 3, 2016.

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1 research

2 people/contact

3 publications

4 protocols

5 opportunities

6 links

7 evolutionary systems biology

8 s cerevisiae

9 ecoli

10 lab news

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Kryazhimskiy lab | sklab.science Reviews

https://sklab.science

Kryazhimskiy Lab @ UCSD. We are interested in uncovering general principles of how mutations affect phenotypes at multiple levels of biological organization (gene expression, metabolic fluxes, etc.), and how these effects combine to determine organism’s fitness across environments. We approach this problem using experiments in model microorganisms. Soon) and mathematical modeling. October 20, 2016. October 11, 2016. First SK Lab meeting! Georg presents his future project. October 3, 2016.

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sklab.science

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UCSD Division of Biological Sciences. UCSD Quantitative Biology Ph.D. specialization (qBio). BLOG Thoughts for breakfast. Kryazhimskiy Lab @ UCSD.

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People

http://www.sklab.science/people

Sergey Kryazhimskiy, PhD. Muir Biology Building 3258 (office), 3165 (lab). Section of Ecology, Behavior and Evolution. Division of Biological Sciences. La Jolla, CA 92093. T: (858) 822 3796. E: skryazhi at ucsd dot edu. Shohreh Hajizadeh, PhD. E: shsikaroodi at ucsd dot edu. Georg Rieckh, PhD. E: grieckh at ucsd dot edu. Sandeep Venkataram, PhD. E: sandeepvenkataram at ucsd dot edu. E: amartsul at ucsd dot edu. Undergraduate students and volunteers. Zoe Ge (high school student). Kryazhimskiy Lab @ UCSD.

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Opportunities

http://www.sklab.science/opportunities

We are currently looking for. We are currently not looking for undergraduate students. We are looking for an enthusiastic graduate student with a quantitative background (e.g., qBio, physics, math majors) to join the lab. There are several exciting theoretical and computational questions on the evolution of populations on fitness landscapes. Contact Sergey Kryazhimskiy (skryazhi at ucsd) with your CV and brief description of your interests. We are currently not looking postdocs. Kryazhimskiy Lab @ UCSD.

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News archive

http://www.sklab.science/news-archive

Kryazhimskiy Lab @ UCSD. October 20, 2016. First Microbial Experimental Evolution and Ecology (MEEE) meeting, a joint meeting between Daugherty, Dutton, Kryazhimskiy, and Meyer labs. October 11, 2016. First SK Lab meeting! Georg presents his future project. October 3, 2016. Dr Sandeep Venkataram arrives from the Bay Area and joins the lab as a postdoc. September 30, 2016. Hang Su finishes her internship. She made progress on RNAseq data analysis and the epistasis theory project. September 19, 2016. June ...

5

Publications

http://www.sklab.science/publications

Rice DP, Jerison ER, Desai MM. 2014) Global epistasis makes adaptation predictable despite sequence-level stochasticity. 344: 1519 1522 (Covered in Quanta Magazine. Rice DP, Desai MM (2012). Population subdivision and adaptation in asexual populations of. Plotkin JB (2009). The dynamics of adaptation on correlated fitness landscapes. Proc Natl Acad Sci USA. Papers in preparation/ submitted/ in review. 2015) Propagation of epistasis through metabolic networks. Jerison ER Kryazhimskiy S. Rice DP, Desai MM ...

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skryazhi | Thoughts For Breakfast

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Some topics that two scientists chat about. Quantitative evolutionary biologist working as a postdoc at Harvard University. Hiring postdocs: the PI perspective. March 11, 2016. Yesterday NatureJobs published an article titled Group dynamics: A lab of their own. It talks about how research group size and composition relate to scientific productivity. This is an important question, which I spent a little bit of time thinking about. In particular, about two years ago I wrote this post. Now, fast forward to ...

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Kryazhimskiy Lab @ UCSD. We are interested in uncovering general principles of how mutations affect phenotypes at multiple levels of biological organization (gene expression, metabolic fluxes, etc.), and how these effects combine to determine organism’s fitness across environments. We approach this problem using experiments in model microorganisms. Soon) and mathematical modeling. October 20, 2016. October 11, 2016. First SK Lab meeting! Georg presents his future project. October 3, 2016.

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